M2 proton channel

Pathways Recommended:	Membrane Transporter/Ion Channel

By Targets:	Apoptosis (3) Bcl-2 Family (2) CDK (2) Influenza Virus (3) Isotope-Labeled Compounds (1) Orthopoxvirus (3) SARS-CoV (3)
By Research Areas:	Cancer (4) Infection (4) Neurological Disease (4)

Targets Recommended: Proton Pump Chloride Channel Calcium Channel HCN Channel CRAC Channel TRP Channel Sodium Channel Potassium Channel Piezo Channel

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0402S

Amantadine-d15 1-Adamantanamine-d₁₅; 1-Aminoadamantane-d₁₅	Influenza Virus Orthopoxvirus SARS-CoV Apoptosis	Infection Neurological Disease Cancer
Amantadine-d₁₅ is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent[1][2].

HY-B0402A

Amantadine hydrochloride 2 Publications Verification 1-Adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride	Influenza Virus Orthopoxvirus SARS-CoV Apoptosis Bcl-2 Family CDK	Infection Neurological Disease Cancer
Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti-orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .

HY-W653905

Amantadine-d15 hydrochloride	Isotope-Labeled Compounds	Infection Neurological Disease Cancer
Amantadine-d₁₅ hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .

HY-B0402B

Amantadine sulfate 1-Adamantanamine sulfate; 1-Aminoadamantane sulfate	Influenza Virus Orthopoxvirus SARS-CoV Apoptosis CDK Bcl-2 Family	Infection Neurological Disease Cancer
Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .

Species:	Virus (3)
Tag:	His (3) Myc (1)
Source:	E. coli Cell-free (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P702368

	Matrix protein 2 Protein, Influenza A virus (Cell-Free, His, Myc) Matrix protein 2; proton channel protein M2	Virus	E. coli Cell-free
	Matrix protein 2 (M2) forms a proton-selective ion channel that efficiently releases the viral genome during viral entry. Matrix protein 2 Protein, Influenza A virus (Cell-Free, His, Myc) is the recombinant Virus-derived Matrix protein 2 protein, expressed by E. coli Cell-free , with N-10*His, C-Myc labeled tag. The total length of Matrix protein 2 Protein, Influenza A virus (Cell-Free, His, Myc) is 97 a.a., with molecular weight of 18.6 kDa.

HY-P702369

	Matrix protein 2 Protein, Influenza A virus 1935 H1N1 (Cell-Free, His) Matrix protein 2; proton channel protein M2	Virus	E. coli Cell-free
	Matrix protein 2 (M2) forms a proton-selective ion channel that is critical for the release of the viral genome during viral entry. Matrix protein 2 Protein, Influenza A virus 1935 H1N1 (Cell-Free, His) is the recombinant Virus-derived Matrix protein 2 protein, expressed by E. coli Cell-free , with N-6*His labeled tag. The total length of Matrix protein 2 Protein, Influenza A virus 1935 H1N1 (Cell-Free, His) is 97 a.a., with molecular weight of 15.1 kDa.

HY-P702370

	Matrix protein 2 Protein, Influenza A virus 1934 H1N1 (Cell-Free, His) Matrix protein 2; proton channel protein M2	Virus	E. coli Cell-free
	Matrix protein 2 (M2) is at the core, forming a proton-selective ion channel that is critical for efficient release of the viral genome during entry. After attaching to the cell surface, virions undergo endocytosis and activate M2 ion channels in endosomes. Matrix protein 2 Protein, Influenza A virus 1934 H1N1 (Cell-Free, His) is the recombinant Virus-derived Matrix protein 2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of Matrix protein 2 Protein, Influenza A virus 1934 H1N1 (Cell-Free, His) is 97 a.a., with molecular weight of 12.5 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-B0402S

Amantadine-d15
Amantadine-d₁₅ is the deuterium labeled Amantadine. Amantadine (1-Adamantanamine) is an antiviral agent with activity against influenza A viruses. Amantadine blocks the proton flow through the M2 ion channel (M2 proton channel of influenza A) and thus prevents the release of viral RNA into the cytoplasm of the infected cells. Amantadine is an antiparkinsonian agent[1][2].

HY-W653905

Amantadine-d15 hydrochloride
Amantadine-d₁₅ hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .

Amantadine-d15 hydrochloride

Amantadine-d₁₅ hydrochloride is deuterated labeled Amantadine. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .

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